| Date | Location | Result | |
| 03/12/22 | Glenville, WV (Waco Center) | Charleston (WV) 52, California (PA) 34 | Box score |
| 03/11/22 | Glenville, WV (Waco Center) | California (PA) 52, IUP 51 | Box score |
| 03/06/22 | Kutztown, PA (Keystone Arena) | Gannon 59, California (PA) 47 | Box score |
| 03/05/22 | Kutztown, PA (Keystone Arena) | California (PA) 78, Shepherd 49 | Box score |
| 03/02/22 | California, PA (Convocation Center) | California (PA) 72, Edinboro 48 | Box score |
| 02/26/22 | Erie, PA (Highmark Events Center) | California (PA) 63, Gannon 57 | Box score |
| 02/23/22 | California, PA (Convocation Center) | California (PA) 75, Mercyhurst 54 | Box score |
| 02/21/22 | California, PA (Convocation Center) | California (PA) 62, Slippery Rock 45 | Box score |
| 02/19/22 | California, PA (Convocation Center) | California (PA) 62, Clarion 42 | Box score |
| 02/16/22 | Greensburg, PA (McKenna Center) | California (PA) 60, Seton Hill 51 | Box score |
| 02/14/22 | Johnstown, PA (Sports Center) | California (PA) 61, Pitt-Johnstown 40 | Box score |
| 02/12/22 | California, PA (Convocation Center) | California (PA) 78, Edinboro 42 | Box score |
| 02/09/22 | Indiana, PA (Kovalchick Complex) | California (PA) 64, IUP 59 | Box score |
| 02/07/22 | Shepherdstown, WV (Butcher Center) | Shepherd 76, California (PA) 66 | Box score |
| 02/05/22 | Erie, PA (Mercyhurst Athletic Center) | California (PA) 68, Mercyhurst 60 | Box score |
| 02/02/22 | California, PA (Convocation Center) | California (PA) 56, Pitt-Johnstown 42 | Box score |
| 01/31/22 | California, PA (Convocation Center) | California (PA) 62, IUP 46 | Box score |
| 01/29/22 | Slippery Rock, PA (Morrow Field House) | California (PA) 66, Slippery Rock 45 | Box score |
| 01/26/22 | California, PA (Convocation Center) | California (PA) 62, Seton Hill 56 | Box score |
| 01/24/22 | California, PA (Convocation Center) | Gannon 61, California (PA) 54 | Box score |
| 01/19/22 | Clarion, PA (Tippin Gymnasium) | California (PA) 71, Clarion 47 | Box score |
| 01/15/22 | Edinboro, PA (McComb Fieldhouse) | Edinboro 62, California (PA) 53 | Box score |
| 12/19/21 | California, PA (Convocation Center) | California (PA) 59, Millersville 46 | Box score |
| 12/18/21 | California, PA (Convocation Center) | California (PA) 97, West Chester 60 | Box score |
| 12/11/21 | Bowie, MD (A.C. Jordan Arena) | California (PA) 64, Bowie State 41 | Box score |
| 12/04/21 | E. Stroudsburg, PA (Koehler Fieldhouse) | California (PA) 69, East Stroudsburg 29 | Box score |
| 12/03/21 | Bloomsburg, PA (Nelson Field House) | Bloomsburg 59, California (PA) 58 (OT) | Box score |
| 11/22/21 | California, PA (Convocation Center) | California (PA) 80, Central State 40 | Box score |
| 11/18/21 | California, PA (Convocation Center) | California (PA) 96, Fairmont State 66 | Box score |
| 11/14/21 | Erie, PA (Mercyhurst Athletic Center) | California (PA) 63, Charleston (WV) 54 | Box score |
| 11/13/21 | Erie, PA (Mercyhurst Athletic Center) | California (PA) 76, West Liberty 60 | Box score |